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| 肺诺卡菌病误诊肺结核1例并文献复习 |
| A case of pulmonary nocardiosis misdiagnosed as pulmonary tuberculosis and literature review |
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| DOI：10.3969/j.issn.1007-8134.2023.03.018 |
| 中文关键词: 肺诺卡菌病 感染 肺结核 误诊 |
| 英文关键词: pulmonary nocardiosis infected pulmonary tuberculosis misdiagnosis |
| 基金项目:海南省科学技术厅项目（ZDYF2021SHFZ228） |
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| 中文摘要: |
| [摘要]?诺卡菌属于较为罕见的人类病原体，主要通过创伤侵入或吸入方式感染。其感染多见于免疫缺陷，特别是细胞免疫缺陷人群，以肺诺卡菌病最为常见。诺卡菌侵袭性及播散性强，易通过血行播散至其他部位，影像学上可符合血型散播疾病特点，且染色及形态特征与分枝杆菌类似，常误诊为结核分枝杆菌感染。本文对1例以咳嗽、咳痰为主要表现，经抗痨治疗效果欠佳，后明确为北京诺卡菌感染并经治好转的病例进行报道，旨在提高临床医生对本病的认识，减少误诊和漏诊。 |
| 英文摘要: |
| [Abstract] Nocardia is a relatively rare human pathogen infected mainly through wound invasion or inhalation. Nocardia infection tends to occur in immunocompromised people, especially those with cellular immunodeficiency, and the pulmonary nocardiosis is the most common disease. With high aggressiveness and dissemination, Nocardia is easily spread to other tissues through blood, meeting the characteristics of blood-type spread diseases on imaging. The staining and morphological characteristics of Nocardia are similar to Mycobacterium, so it is often misdiagnosed as Mycobacterium tuberculosis. Here we reported a case of cough and expectoration and poor response to anti-tuberculosis treatment, which was subsequently diagnosed as Nocardia Beijing infection and improved after etiological treatment, aiming to improve clinicians’ understanding of this disease and reduce the misdiagnosis and missed diagnosis. |
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