| [Abstract]?Objective?To analyze the clinical characteristics of brucellosis complicated with infectious aortic aneurysm, so as to improve the clinical knowledge and treatment level of this disease. Methods? Nine cases of patients with brucellosis complicated with infectious aortic aneurysm admitted to Beijing Anzhen Hospital from January 1, 2002 to June 1, 2022 were selected as research objects, epidemiological data, clinical manifestations, laboratory results, imaging data, treatment and prognosis were collected. Results?Among the 32 cases of Brucella infection confirmed by blood culture, 9 cases were complicated with aortic aneurysm, and the incidence was 28.13%. Among them, 8 cases were male and 1 case was female, aged 58-75 years. There were 3 cases with a clear history of cattle and sheep contact, 1 case with a history of unclean goat milk drinking, and 1 case with a history of tourism in pastoral areas. All patients had a fever, and 1 case had a typical wave fever. The main symptoms of the patients were lumbar and abdominal pain, which was misdiagnosed as lumbar tuberculosis in 2 cases, and lumbar spinal stenosis in 3 cases. One patient was complicated with epididymitis. The abdominal aorta was involved in 6 cases, ascending aorta in 1 case, and the aortic arch in 2 cases. The serum agglutination test was positive in all 9 patients. All 9 patients received rifampicin, doxycycline, and levofloxacin anti-infective therapy. Except for 1 patient who was lost to follow-up, the remaining 8 patients were treated for 3-6 months. Among the 7 patients undergoing surgical treatment, 6 patients underwent aortic replacement or repair, and 1 patient underwent stent implantation after 6 months of anti-infection treatment. All the patients were followed up for 5 months to 7 years (median time: 4 years). One patient died of a cerebrovascular disease accident 5 years after surgery, and the other 6 patients survived. Among the 2 patients who did not receive surgical treatment, 1 patient lost the follow-up after discharge, and 1 patient survived for 3 years. Conclusions?Aortic involvement in brucellosis is rare and life-threatening. The lack of understanding of this disease easily to leads to missed diagnosis and misdiagnosis. The cornerstone of the treatment of this disease is still anti-infection treatment combined with open surgery. The role of interventional surgery such as endovascular stenting has not been determined, so it is necessary to consider the patient’ s condition and the risk of long-term complications. |