|
| 老年HIV/AIDS患者衰弱综合征的研究进展 |
| Research progress of frailty syndrome in aging people with HIV/AIDS |
| |
| DOI：10.3969/j.issn.1007-8134.2022.03.018 |
| 中文关键词: 人类免疫缺陷病毒 艾滋病 抗反转录病毒治疗 衰弱 老年综合征 机制 干预措施 研究进展 |
| 英文关键词: HIV AIDS ART frailty geriatric syndromes mechanism intervention research progress |
| 基金项目:“十三五”国家科技重大专项（2018ZX10721-102-003-003，2018ZX10302-102）；北京市科技计划课题（Z211100002921003）；北京市自然科学基金（7222092） |
|
| 摘要点击次数: 329 |
| 全文下载次数: 0 |
| 中文摘要: |
| [摘要]?衰弱综合征（衰弱）是一种由机体退行性改变和多种慢性疾病引起的机体易损性增加的综合征，与临床不良结局密切相关，严重影响HIV/AIDS患者的身体功能和生存质量。抗反转录病毒治疗（anti-retroviral therapy, ART）有效抑制了HIV复制，延长了感染者寿命，加速了HIV/AIDS患者的老龄化趋势。本文围绕老年HIV/AIDS患者衰弱的流行病学特征、可能机制以及应对措施进行综述，为老年HIV/AIDS患者衰弱的早期识别和及时干预提供参考。 |
| 英文摘要: |
| [Abstract] Frailty syndrome is a syndrome with increased vulnerability caused by degenerative changes of the body and multiple chronic diseases, which is closely associated with adverse clinical outcomes and severely affects the physical functioning and life quality of people living with HIV/AIDS. Antiretroviral therapy (ART) has been proven to be effective in suppressing HIV replication and extending the life expectancy of HIV-infected individuals, accelerating the aging of HIV/AIDS patients. Therefore, the early identification and timely intervention of frailty can be promoted by an in-depth study on its epidemiological characteristics, potential mechanisms, and treatment strategies for those aging patients with HIV/AIDS. |
|
HTML
查看全文
下载PDF阅读器 |
| 关闭 |