| To clarify the influencing factors affecting the outcome of Brucella spondylitis through the analysis of the clinical characteristics and outcome of Brucella spondylitis. Methods A total of 81 patients with Brucella spondylitis admitted to our hospital from May 2016 to May 2018 were selected as the study subjects. The disease course, underlying disease and neurological impairment, as well as laboratory and imaging examination of patients were retrospectively analyzed. Through univariate and multivariate Logistic regression analysis, the relevant factors affecting the effect of drug treatment were screened, and the main influencing factors were identified. Results In the group with unsatisfactory treatment effect, the disease course was＞2 months at admission, and the incidences of neurological impairment, combined with diabetes, arthritis or (and) testosterone were higher than those in the group with satisfactory treatment effect (P＜0.05). In the imaging examination, the incidence of concurrent intraspinal abscess in the group with unsatisfactory treatment effect was higher than that in the group with satisfactory treatment effect (P＜0.05). In the laboratory examination, the incidence of reduced albumin (＜35 g/L) in the group with unsatisfactory treatment effect was higher than that in the group with satisfactory treatment effect (P＜0.05). Diabetes mellitus, concurrent intraspinal abscess, neurological impairment, and disease course of＞2 months were the main influencing factors for unsatisfactory effect of drug treatment (P＜0.05). Conclusions Diabetes, combined intraspinal abscess, neurological impairment and disease course＞2 months are the main factors affecting the medication for Brucella spondylitis, identify the above influecing factors they can help to predict the outcome of the disease and provide a reference for doctors to formulate more active and effective treatment measures. |