| Objective To investigate the distribution and multi-drug resistance of pathogenic bacteria in nosocomial lung infections in patients with colorectal cancer after surgery. Methods Totally 324 patients undergoing colorectal cancer surgery from June 2015 to June 2019 were selected as the subjects. All patients completed postoperative relevant examinations and were evaluated based on the criteria for determining lung infection. Bact/alert 3D automatic bacterial culture instrument was used to complete the bacterial culture and the liquid dilution method was used to complete the drug sensitivity test. Results All 324 patients undergoing colorectal cancer surgery completed the relevant examinations, and 75 patients developed pulmonary infections after surgery, with an infection rate of 23.15%. A total of 38 strains of pathogenic bacteria were isolated from 75 patients with lung infections. The top 3 bacteria were: Klebsiella pneumoniae (32.93%), Acinetobacter baumannii (18.42%) and Pseudomonas aeruginosa (15.79%). Among 38 cultured pathogens, 15 strains were multi-drug resistant, and the top 2 were Klebsiella pneumoniae and Acinetobacter baumannii. The results of multi-drug resistance analysis showed that Klebsiella pneumoniae was mainly resistant to ampicillin and ticarcillin. Acinetobacter baumannii was mainly resistant to amoxicillin/clavulanic acid, ampicillin/sulbactam, ampicillin, chloramphenicol, tetracycline, cefazolin and cephalothin. Pseudomonas aeruginosa was mainly resistant to amoxicillin/clavulanic acid, aztreonam, ampicillin, chloramphenicol, cefazolin and cephalothin. Conclusions The incidence of nosocomial lung infections in patients with colorectal cancer after surgery is relatively high, pathogenic bacteria is widely distributed and multi-drug resistance of pathogens occupies a certain proportion. Sensitive antibiotics should be selected according to the results of drug sensitivity. |