文章摘要
7例北京地区新型冠状病毒肺炎的临床及实验室特征分析
Clinical and laboratory characteristics analysis of 7 cases with COVID-19 in Beijing
  
DOI:10.3969/j.issn.1007-8134.2020.05.008
中文关键词: 新型冠状病毒肺炎  诊断  临床和实验室特征
英文关键词: COVID-19  diagnosis  clinical and laboratory characteristic
基金项目:
作者单位
蔡 珍 中国医科大学航空总医院检验科 
李 伟 中国医科大学航空总医院感染科 
申太忠 中国医科大学航空总医院放射科 
郭 娇 中国医科大学航空总医院检验科 
何宗辉 中国医科大学航空总医院检验科 
李 宝 中国医科大学航空总医院放射科 
张敬霞 中国医科大学航空总医院检验科 
李 晶 中国医科大学航空总医院检验科 
张露方 中国医科大学航空总医院检验科 
陶 佳 宁夏医科大学总医院检验科 
李 敬 中国医科大学航空总医院医院感染控制科 
曲 芬 中国医科大学航空总医院检验科 
沈吉云 中国医科大学航空总医院院办 
周庆明 中国医科大学航空总医院医疗处 
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中文摘要:
      目的 分析由新型冠状病毒感染引起的新型冠状病毒肺炎的临床及实验室特征。方法 回顾性分析2020年1月24日—3月8日在中国医学大学航空总医院接诊并诊断明确的新型冠状病毒肺炎患者相关资料,包括流行病学史、临床特征、影像学及实验室检查数据。结果 2020年1月24日—3月8日,中国医学大学航空总医院共筛查76例发热患者,7例确诊为新型冠状病毒肺炎。7例患者均有武汉旅居史或与武汉返程人员接触史,4/7的患者年龄在41~65岁,4/7的患者合并基础性疾病。所有患者均为轻型或普通型,6/7的患者有发热症状,4/7的患者有咳嗽或咽痛症状,没有患者出现腹泻或呼吸困难。影像学结果表明,6/7的患者胸部CT均存在大小不等团片状磨玻璃影,其内均可见细密网格影,至少有1处病变紧贴胸膜。实验室检查结果表明,3/7患者淋巴细胞计数减少,4/7患者CRP升高,3/6患者D-二聚体升高。7例患者新型冠状病毒核酸检测均为阳性,经抗病毒及对症治疗治愈。结论 新型冠状病毒肺炎症状因人而异,该疾病的诊断应综合患者的流行病学史、临床表现、CT及实验室检查结果等信息。
英文摘要:
      Objective To analyze clinical and laboratory characteristics of COVID-19 caused by SARS-CoV-2. Methods Data of COVID-19 patients who were admitted to and definitely diagnosed in Aviation General Hospital of China Medical University from January 24, 2020 to March 8, 2020 were retrospectively analyzed, including epidemiology history, clinical characteristics, imaging and laboratory test data. Results From January 24, 2020 to March 8, 2020, a total of 76 fever patients were screened in Aviation General Hospital of China Medical University and 7 cases of them were confirmed as COVID-19. All of 7 patients had a history of direct or indirect contact with people living in Wuhan and returned from Wuhan, 4/7 of patients aged ranging 41-65 years old, 4/7 of patients had underlying diseases. All of 7 patients was clinically mild or common cases, 6/7 of patients had symptom of fever and 4/7 of patients had symptom of cough or throat pain. None of patients appeared diarrhea or dyspnea. Imaging results showed that 6/7 of patients had patchy ground-glass opacities of varying sizes, with fine mesh shadow, and at least one lesion appeared at pleural region of lung by chest CT. Laboratory test results showed that 3/7 of patients had decreased lymphocytes, 4/7 of patients had increased CRP and 3/6 of patients had increased D-dimer. All of patients presented positive results of nucleic acid test for COVID-19. All of patients were successfully cured by antiviral and symptomatic treatment. Conclusions COVID-19 symptoms vary among individuals. COVID-19 diagnosis should be made based on the information of epidemiology history, clinical manifestations, CT and laboratory test results.
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