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| 一起由柯萨奇病毒A6型引起的疱疹性咽峡炎暴发疫情调查分析 |
| Survey on a herpangina outbreak caused by Coxsackievirus A6 |
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| DOI：10.3969/j.issn.1007-8134.2020.03.013 |
| 中文关键词: 疱疹性咽峡炎 柯萨奇病毒A6型 暴发 |
| 英文关键词: herpangina Coxsackievirus A6 outbreak |
| 基金项目:北京市西城区卫生与计划生育青年科技人才培养项目（XWKX2018-23） |
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| 中文摘要: |
| 目的 了解北京市某中学一起疱疹性咽峡炎暴发疫情的流行特征，为疱疹性咽峡炎的防控提供科学依据。方法 对病例开展个案调查，采集咽拭子标本进行检测，采用描述性流行病学方法对疫情的流行病学特征和临床特点进行分析。结果 2017年10月11日—11月2日，北京市某中学累计报告疱疹性咽峡炎病例92例，罹患率2.39%。临床表现以口腔疱疹（92.39%）、咽痛（71.74%）、发热（69.56%）为主。共采集43例病例咽拭子标本进行检测，24例柯萨奇病毒A6型阳性，6例肠道病毒未分型阳性。结论 本起暴发疫情是由柯萨奇病毒A6型感染引起，学生交叉上课、共用餐厅等公共场所导致疫情的传播，探索一套适应教育改革后传染病的防控方案势在必行。 |
| 英文摘要: |
| Objective To analyze the epidemiological characteristics of a herpangina outbreak occurred in a middle school of Beijing, and provide scientific evidence for epidemic control. Methods An individual survey was performed among all cases. Throat swab specimens from all cases were subjected to detection. Descriptive epidemiological methods were used to analyze the epidemic characteristics and clinical features of the epidemic. Results A total of 92 cases were reported from October 11 to November 2, 2017 in a middle school of Beijing, and the attack rate was 2.39%. The clinical manifestations of affected cases included oral herpes (92.39%), pharyngalgia (71.74%) and fever (69.56%). Totally 43 throat swab specimens were collected, 24 positive for Coxsackievirus A6 and 6 positive for untyped enteroviruses. Conclusions The herpangina outbreak is caused by Coxsackievirus A6. Cross-class, sharing restaurants and other public facilities leads to the outbreak in students. It is imperative to explore a series of procedures for prevention and control of infectious diseases after educational reform is carried out. |
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