|
| 高效抗反转录病毒治疗双药简化方案的研究进展 |
| Recent advances in dual-drug simplified regimens for highly active antiretroviral therapy |
| |
| DOI：10.3969/j.issn.1007-8134.2019.06.020 |
| 中文关键词: 人类免疫缺陷病毒 高效抗反转录病毒治疗 双药简化方案 |
| 英文关键词: human immunodeficiency virus highly active antiretroviral therapy dual-drug regimens |
| 基金项目:“十三五”国家科技重大专项课题（2017ZX10202101-003）；广州市科技创新委员会健康医疗协同创新重大计划课题（滚动）项目（201803040002） |
|
| 摘要点击次数: 612 |
| 全文下载次数: 404 |
| 中文摘要: |
| 高效抗反转录病毒治疗三联方案是治疗HIV感染的主流，然而，随着治疗人群扩大到所有HIV感染者，以及治疗时间延长，人们对高效、高依从性、低不良反应、低耐药及低治疗成本方案的需求日益增加，双药简化治疗成为个性化治疗的备选方案，一些方案已经被纳入国内外抗病毒治疗指南。本文对近年来双药简化方案的发展进行综述，为临床正确应用该方案提供依据。 |
| 英文摘要: |
| Triple-drug regimens for highly active antiretroviral therapy (HAART) are the main treatment strategy for HIV in most countrins. As all HIV-infected patients have received HAART and treatment time has prolonged, the demand for treatment with high effectiveness, high adherence, low adverse effects, low drug resistance and low cost continuously increases. Dual-drug simplified regimens provide plenty of alternatives for individualized HIV treatment and some have been included in the antiviral treatment guidelines in China and at abroad. In this study, we systematically review the recent advances in dual-drug regimens for HIV treatment and provide evidence for clinical applications of dual-drug regimens. |
|
HTML
查看全文
下载PDF阅读器 |
| 关闭 |