| Objective To study the effect of group B Streptococcus (GBS) infection on pregnancy outcomes of pregnant women in late pregnancy. Methods One hundred and sixty prepartal women at gestational 35-37 weeks who received prenatal examination in Beijing Jishuitan Hospital from June 2016 to August 2018 were included in this study, to collect their vaginal secretions and perianal secretions. Quantitative fluorescence polymerase chain reaction and bacterial culture method were used to screen the secretions. According to the results, they were divided into GBS positive group and GBS negative group. The effects of GBS infection on pregnancy outcome were analyzed. Results Among the included 160 pregnant women, there were 82 GBS positive cases, and the positive rate of GBS was 51.25% (82/160). There were no significant differences in the age, gestational week and parity between the 2 groups (P＞0.05). The incidences of postpartum hemorrhage (40.24%), premature rupture of membranes (20.73%) and intrauterine infection (24.39%) in the GBS positive group were higher than those in the GBS negative group (P＜0.05). Eighty-two strains of GBS were isolated and all were susceptible to penicillin G, ceftriaxone, penbritin, linezolid, accounting for 100%. The susceptibility rates to tetracycline, clarithromycin, vancomycin, levofloxacin, erythromycin and clindamycin were 7.31%, 8.54%, 82.93%, 68.29%, 71.95% and 68.29%, respectively. Conclusions Pregnant women infected with GBS in late pregnancy will increase the incidence of postpartum hemorrhage, intrauterine infection and premature rupture of membranes, thus induce adverse effects on pregnancy outcomes. It is necessary to screen GBS in late pregnancy. |