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| 维持性血液透析艾滋病患者生存期影响因素的探讨 |
| Factors affecting the survival of maintenance hemodialysis AIDS patients |
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| DOI：10.3969/j.issn.1007-8134.2019.06.008 |
| 中文关键词: 维持性血液透析 AIDS 生存期 影响因素 |
| 英文关键词: maintenance hemodialysis AIDS survival period influencing factor |
| 基金项目:南宁市科学研究与技术开发计划项目（20163013）；南宁市科学研究与技术开发计划项目（20183202-1） |
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| 中文摘要: |
| 目的 探讨维持性血液透析（maintenance hemodialysis, MHD）AIDS（MHD-AIDS）患者生存期影响因素，为生存期预判及MHD管理提供参考依据。方法 收集南宁市第四人民医院2011年6月—2017年5月122例MHD-AIDS患者，采集登记透析前基线资料，并对上述患者进行随访，分别采用乘积限法和Cox比例风险回归模型对生存率和危险因素进行评估。结果 MHD-AIDS患者生存率随时间下降，其中半年生存率最高，为68.6%，3年生存率最低，为35.4%。多因素分析表明正常体重、MHD是影响患者生存率的保护因素。结论 MHD-AIDS患者要加强MHD管理，减少影响生存率的危险因素，延长患者的生存期。 |
| 英文摘要: |
| Objective To explore the factors influencing the survival of maintenance hemodialysis (MHD) AIDS (MHD-AIDS) patients and provide a reference for predicting survival and MHD management. Methods A total of 122 patients with MHD-AIDS were enrolled from in the Fourth People’s Hospital of Nanning during June 2011 to May 2017. The pre-dialysis baseline data were collected and the involved patients were followed-up. The survival rate and risk factors were evaluated by using Kaplan-Meier method and Cox proportional hazard model respectively. Results The survival rate of patients with MHD-AIDS decreased with time, with the highest survival rate of 6 months (68.6%) and the lowest survival rate of 3 years (35.4%). Multivariate analysis showed that normal weight and MHD were protective factors affecting the survival rate of patients. Conclusions For MHD-AIDS patients, we should strengthen the management of MHD, reduce the risk factors affecting the survival rate and prolong the survival period of patients. |
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